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Rethinking Current Strategies in Today's Treatment of MDROs

carbapenem-resistant Enterobacteriaceae
Antibiotic Optimization in Today's Hospital Setting:Rethinking Current Treatment Strategies- The pandemic of multidrug-resistant (MDR) bacteria and their continuing spread is beyond dispute, and is now considered a global public crisis. The threat of infections caused by MDR organisms has been well documented over the past decade along with warnings concerning the consequences of inappropriate use of antimicrobials in accelerating resistance development. The newest threat includes the emergence and spread of carbapenem-resistant Enterobacteriaceae.
Clinicians must consider all aspects when designing a treatment plan for combating MDR infections. Inappropriate initial therapy can have significant consequences with respect to patient morbidity, mortality, and overall costs. Therefore, clinicians must utilize the latest strategies in infection control, diagnostics, and antibiotic selection with regimens optimized to ensure the highest probability of achieving a successful outcome. With few effective agents available, there is a pressing need for new management strategies when combating serious bacterial infections. Optimizing antimicrobial therapy based on patient-related, pathogen-related, and drug-related factors is essential in maximizing the probability of successful outcomes.
Evaluate the utility of the latest assays and techniques for diagnosing bacterial infections to guide infection control and treatment decisions.
Differentiate new and emerging therapeutic options for treating multidrug-resistant bacterial infections.
Identify strategies to optimize the use of antimicrobials by considering patient-, pathogen-, and drug-related factors.

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